I take prednisone shot or pills almost once a year. When it's the pill, it's a 10mg pill, but I start with 4 per day and taper off to 1/2 a pill over a span of 2 weeks.

Seriously calms down allergies and eczema. Side effect while taking it: gotta piss frequently like an old man, that's it. It'd be a miracle medicine to me if it didn't have seriously LONG term side effects (liver damage, kills your bones, glocoma, etc etc).