With that much boost, you need to resleeve the block, put in some stronger rods, low compression pistons, strengthen the bottom end a good amount, etc.
Why 25 psi? 25 psi can be completely different things with different sized turbos. You need to decide your power goals before you automatically decide you want to boost 25 psi so that you can find a properly sized turbo that can meet your power goals with much less boost.