I have a feeling it's your torque converter locking. Do a simple test: accelerate to a speed between 30 and 50 MPH. Hold your speed, and then lightly tap on the gas pedal repeatedly, just enough to unlock the torque converter. If this causes your car to jump and it feels really rough, then your TC is bad. There is a TSB for this so if you have low miles you might get consideration. It should be smooth and you should just feel a slight acceleration/hesitation.
When was the last tranny fluid change? Did you use genuine Honda fluid?