Sorry Vassil, i saw your SN, and meant it for the guy posting above you, hothonda18.
I dont know the inside of a Prelude engine bay like clockwork, so i couldnt specifically tell you where the fuel filter is located. However, if you like to run the tank to empty (like myself and many others do) chances are you're bringing up old crap from the bottom of the tank. This is stuff that clogs fuel filters.
Remember, the single most important factor in fuel efficiency and mileage is the driver themselves. You say that preludes are bad on gas, and you only get 17 mpg? thats not very good. I know many people including my brother who drive around mostly in city situations with stop and go (my brother is a delivery guy, uses his lude) and still gets 22 mpg, or close to 325 a tank) if you're averaging low fuel economy and so are your friends, maybe you guys are driving aggressive. You may see it as normal though.
Yankee...if you already have new plugs and wires, check fuel filter, cap,rotor, distributor. Also, check tire pressure. With weather fluctuations, this can change as well. If all else fails, check engine compression and oil consumption.