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Well, if it happens, the quickest way to get rid of it is to streck it. Yes, by putting weight on it. Yes it is difficult to really get yourself to do, but when it's 3am and you somehow do it while sleeping you just don't think about these things.
those things suck so bad, i sometimes get them while sex0ring mah lady h:
this one time when i was at track practice i went to un-tie my shoe and my calf cramped up. my foot stayed pointing downward for a good minute while i screamed in agony. yea...it hurt.