Not really. The issue here is that the LS engine has a lower compression ratio to begin with, so you can push a bit more boost safely. As for VTEC, the issue a lot of people worry about is the cam overlap once you're in VTEC, which doesn't make the turbo work harder, but also doesn't let the engine make full use of the higher pressures. You can correct this issue with turbo cams, going with VTEC killer cams [which just means your VTEC head is no longer VTEC], or even just adjusting your stock cams with cam gears.

Personally if you're worried about not making as much power as you could in VTEC, I'd go with some dedicated turbo cams with or without VTEC in a VTEC head just because the port designs are a bit nicer for air flow.

Bottom line is that you can make tons of power no matter what b-series head you use with a turbo, after that it all depends on how much displacement you want to force feed.