i have 50k miles on 2000 accord coupe V6, besides the one annoying rattle on my right side door, the car is flawless, haven't had a single complain yet.. also just replaced the tires to kumhos and the car is really smooth, especially on bumps.
that all being said, i am having doubts on my tranny, it has erratic shifting, i am going to wait till it falls apart then have it replaced under warranty.