It all depends on your definition of high boost. If 30 lbs. of boost is high for you, then you'll need a fully built block. If your thinking 20 lbs. of boost is high, then all you need is Hondata 4b and blockguard.
The AEM EMS isn't fully developed yet. The software needs to be updated before it can be as beneficial as Hondata. The software is so bad that even people trained by AEM have blown up a few engines.