Well let me first say that I do not own a prelude but I was surfing over here considering the similarity in engines with my 2.2cl (acura). First off it is very possible to swap an h22 in for an f22. Yes it would be very beneficial considering that you would have much more power to work with.

BTW the only difference between your current motor and the CL motor is the the CL'S has v-tec