Looks like a pretty solid team. How many teams in your league? I find that bigger leagues are a bit more fun, because you run out of stars and have to fill some holes with no name guys or people who can play multiple positions.

With a solid roster like you've got, I'd play matchups most weeks. Try to sit people who are going to go against the monster defenses (Steelers, San Diego, etc.) and start the guys going against the scrubs. A couple of weeks in you'll have a better handle on who is going to be having a great year and who the week defenses are. Due to bye weeks and injuries, you often won't even have to make decisions about who to start because you'll only have 1 guy available.

As far as stats go, just keep an eye on who is getting a lot of points each week and remember that Touchdowns are more important than yards. For example, Vernon Davis doesn't get a ton of yards, but he's a favorite redzone target, so he's good to start. My favorite example of this is BenJarvus GreenEllis (sp?) on the Patriots. They love to use him in the red zone but very rarely otherwise. His stats for the game will often be 28 yds, 2 TDs or something similar.

I think you've got a good lineup for your first week. I wouldn't change any of the guys you have starting. But make sure to check your lineup on Thursday and early Sunday morning -- sometimes last minute injuries happen (even before week 1) and you don't want to have anybody starting who isn't going to play that day.

Edit -- nvm, you don't have anyone playing in Thursday's game so you won't have to check in on Thurs. h:

Also, does your league get points for special teams yardage? Picking up a good punt/kick returner can be a good backup guy, as they are often listed as both WR/RBs and can be a good guy to have around in case one of your main guys goes down.