there is a big difference, yes.
since your GS-R is still new, i would recommend using synthetic. there are stories that high milage engines tend to leak when they switch to synthetic. don't know if it's true, but i don't want to risk it, which is why i'm still on conventional. but i would much prefer synthetic.
anyway, yes, synthetic protects better. you can go longer between oil changes.. etc etc..
lots of benefits.. tonight i'll try to go into more detail if someone doesn't go first (busy at work)..