I've never done that, never even thought of it before (:rick

but I doubt I'd go to the hassle unless it was a significant difference. Since it's unopened though, and they aren't losing money on reselling the item, do as you will.
Returning opened stuff though for similar reasons I'd feel too guilty about to do. I've returned opened games before, but always to the same place (all require receipts around here) and usually for another copy of the same game. They often would open the new game before giving it to me too, probably thought I was trying to scam them.