I have a set of Skunks on Tokico Blues, lowered about 2-1/2" and I have a set of 16x7 wheels with a +37mm offset mated with 205/40/16's and I experience no rubbing whatsoever. None during bumps or hard turns. I've yet to experience 45 series tires so I'm not sure if those would rub.

Right now, the car is sitting on stock steelies with 205/50/15's and with the same height and it's the same result. No rubbing whatsoever.