There's no reason to. You won't really gain much at all, it's not worth the $ in my opinion. Plus, you'd have to buy new rings, bearings, rods, etc...not just the pistons. You might gain a couple hp...but that's about it. Replacing pistons is more about strengthening the bottom end for boost/nitrous/high compression/high rpm.
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2015 Ford Mustang GT Fastback - Ingot Silver - 6M - Performance Package - Gibson Catback, JLT CAI, FR 47lb injectors, BAMA E85 tune, Eibach Sportline, BMR wheel hop kit, UPR oil separator, Steeda shifter bushing/bracket
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