The bleeder bolt should be visible without having to remove anything else to get to it. Just use a 1/4 drive 12mm socket with a long extension. I mean it's not buried or anything. Sealant on the block plug is a good idea, but NOT on the radiator drain plug, because it is plastic and has an o-ring of its own. Other than that...nothing to it, and good luck.
Oh btw, there is a trick I learned for bleeding the system when I was still working for Honda. I don't suppose you have a spare CV boot laying around do you? I would slip the narrow end of the boot over the radiator cap fitting, fill the radiator, and let the engine run until the fans come on. Using this method I never even had to use the bleeder screw. Yes the boot will be full of coolant, so when the fans come on, pull the boot off and put the radiator cap back on.