the auto trans has it's own controller. it may be something wrong with that. the VSS and cruise runs though it if I remember right.
For the record... a dead VSS would cause all of those things also.

dead speedometer - no signal
odometer - same drive as speedo
no cruise control - what speed should it set???
no overdrive - how does it know that you're going fast enough to engage it?

what year/type of honda are we talking about here? I may be able to help you though it.