Honestly, with a Prelude a h22 is your best choice. An Accord V6 is theoretically possible but you'd be looking at a lot of fab work.
If you are really insistant on removing VTEC you can eliminate it instead of swapping heads. The nonVTEC heads flow like crap, frankly. However, even on high horsepower setups the head is the least of your worries.
VTEC is unneccessary on a vehicle purpose built for racing. However, its elimination is typically done to minimize mass, not due to breakages.