I think Nader accomplished a great deal with his book Unsafe at Any Speed. He ended the era of Detroit's "devil-may-care attitude", which came to a head with the Corvair - which truly was a dangerous, ill-designed product.

And despite this, I simply cannot connect with his platform in the 21st Century.

He's way outside the political mainstream, and - for me - he's direly lacking in charisma. His cohorts, Claybrook and Ditlow are not my favorites either.

If you can't connect to your consitituents, there's little point in running at all. h:
Historically, 3rd party candidates - with the exception of H. Ross Perot - have not shown much skill in drawing a statistically significant number of votes.

So in short, no. He's certainly entitled to run for office, but he's always been a longshot.