mr-s is also a lot smaller. i have driven one on a 60 mile trip and i truely felt cramped (im only 5'10") but in my s2000 i felt more comfortable (50 hour trip from minnesota to texas and back) for everything. but of course price still comes into fact. the mr-s cheaper then the s2000 but its been said before ur giving up things on that too.
choice is yours. best bet would be to drive both and choose which ever feels the most comfortable.