Sure, it will work... but, you must make sure that the output voltage of your laptop (that stereo mini plug) is within the amplifier's operating input voltage to avoid clipping of the audio signal. That's not good. I'm confident that it will be ok. Now, a couple caveats... 1) The only way to adjust the volume is by the source unit... your laptop not your radio. 2) The only way to switch between your radio & your laptop is to switch wires.