Both the 225/45-15 and the 225/50-15 will fit the ITR 15x6 rims.
I know from experience that the 225 Victo's require a spacer to prevent the tire from rubbing. I'd be willing to bet that the 225's from Hoosier also require the spacers. The spacers that I use are 5mm.
What are you using the 225's for? Most DS cars are running 225's front and 205's rear.
I hope this helps.