Some of the fastest turbo hondas are high compression. The higher compression just leaves less room for error in tuning. With a good tuner a high compression turbo setup is very possible. The main things to be concerned about is engine knock and high engine temperatures.

If i was to personally build another turbo setup i would go the low compresion rate. Yes it wont make the same power as another engine at the same psi but i can make up for that with more psi. You can make just as much power as a higher compression motor with less worries, except for those who worry about higher psi's.