i'll speak on behalf of WiLL, DB7 2.0 and myself.

We all have non-vtec motors in our integras, as well as 4-1 headers. We've all found a loss in low-end torque, and noticable gains on the upper half of the RPM range.

If you're looking for just highway cruising and around the town driving, go for the 4-2-1, otherwise go for the 4-1 if you're okay with losing some low-end torque.