I used to use it, but it was on my old 89 Accord Coupe (200 shot programable nitrous system, it was alot of fun till it went BOOOMMM!!!!)

I have a friend with a 2000 Accord V6 and if I remember correctly he is using a 45 shot. His only other mods are cold air intake and exhaust and he has been using the nitrous for about a year and a half. Car still runs like new.