some good paint, a good gun, a VERY and I mean
VERY clean environment to paint in. One fleck of dust will ruin your whole day. Other than that, light coats is the key. If you don't make it with one pass, you always have another, then a real good wetsanding session followed by a good sealer(clear) and you're all set. A few tips, clean, clean and more clean. Any oil like if you accidently bruch your arm on the car when preping it will cause a fish eye, If your clothes make link, wear a painters suit. Always, and I mean always wear a respriator and some eye protection.
It's best left up to the pro unless you'd had some training on it, don't attempt it yourself without having a pro walk you through it. And even after that I'd practice on a few junkers before you try a serious car.
what do you mean serious money, a earl shybe, or maaco, or one of the discount paint places, it's not a great job, but it's far better than you could do by yourself, and doesn't cost that much. a good paint gun will cost more than an entire good paint job. The gun I used cost close to $5000 but oh did house of kolor flow through it's veins