no, unless you plan on making regular 160+ mph runs.
The shorter the gears the better, it's not going to hurt your motor down the highway as long as you stay off the high lift cam profile, which mean you can cruise all day at 90-100 without worrying, just don't skimp on oil changes or regular maintenance, it shouldn't overheat, the short fifth is nice for some passing oomph, no need to downshift.